OpenMemory

E2B provides JavaScript and Python SDKs for starting isolated cloud sandboxes where agents can execute commands or generated code without running directly on the host. The managed service requires an E2B API key, and a separate Code Interpreter package adds higher-level code execution. Self-hosting is documented through Terraform, with current provider support centered on AWS and Google Cloud.

Cloudflare Agents uses Durable Objects to give each agent its own persistent state, storage, and lifecycle. The SDK includes callable methods, WebSockets, scheduling, AI chat, MCP, and workflow integration, with client helpers for real-time synchronization. Developers can start from the provided template or add the package to an existing Cloudflare application.

Create general-purpose agents in TypeScript with streamed events, filesystem or shell tools, persistent multi-turn sessions, and middleware for compaction, retry, and turn tracking. The SDK also covers subagents, MCP servers, on-demand skills, virtual filesystems, and React or Vue chat integration on top of Vercel's AI SDK.

Composio creates a separate session for each user and gives an agent runtime access to app authentication, tool discovery, and execution without loading hundreds of definitions into context. It offers TypeScript and Python SDKs, a CLI, framework adapters, and hosted MCP endpoints for more than 1,000 app toolkits. Setup requires a Composio API key and the relevant connected user accounts.