composio

Semantic Kernel is a model-agnostic SDK for building, orchestrating, and deploying AI agents and multi-agent systems across Python, .NET, and Java. It supports multiple model providers, plugins, structured workflows, and vector-database integrations. The project now identifies Microsoft Agent Framework as its successor and provides a migration guide, which is relevant when maintaining or starting an application.

OpenAI Agents SDK lets Python developers define agents with instructions, tools, guardrails, and delegation between specialized workers. It includes session history, human approval points, tracing, sandboxed long-running agents, and realtime voice support. The framework can use OpenAI APIs or other supported model providers and requires Python 3.10 or newer.

Claude Agent SDK for Python exposes an async query function and ClaudeSDKClient for bidirectional, interactive conversations with Claude Code. Custom tools and hooks can run as in-process MCP servers, while external MCP servers can be used alongside them. The package bundles the Claude Code CLI by default, requires Python 3.10 or newer, and allows a custom CLI path.

Strands Agents is a monorepo with Python and TypeScript SDKs for building model-driven agents. The SDKs support tools, MCP, streaming, multi-agent patterns, hooks, guardrails, context management, and multiple model providers, with examples for local development and deployment. Python requires 3.10 or newer and the TypeScript package requires Node.js 20 or newer; the default quickstart uses Amazon Bedrock credentials.